Claire
Is this in regard to your PIP appeal?
Yes, you can make a new claim PIP now, you don't need to cancel your appeal but the Decision that will result from the new claim will limit any award that a Tribunal might make.
You will need to consider how you address the problems that meant that your previous claim failed, or you will likely receive the same Decision.
Gordon
Nothing on this board constitutes legal advice - always consult a professional about specific problems